Isotopically Labeled Compounds
Medchemexpress LLC Urea-d4 | 1433-11-0 | MFCD00044227 | 100.0% | 64.08 g/mol | CD4N2O | 1g
Urea-d4 is the deuterium labeled Urea[1] Urea is a powerful protein denaturant via both direct and indirect mechanisms[2] A potent emollient and keratolytic agent[3] Used as a diuretic agent Blood urea nitrogen (BUN) has been utilized to evaluate renal function[4] Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry
Genscript Corporation 25-OH Vitamin D3 BSA Conjugat
Vitamin D plays an important role in calcium homeostasis and metabolism Vitamin D3 and vitamin D2 are two forms of vitamin D in human body both of which only a few foods contain The deficiency of vitamin D in human body can cause a threat of diseases such as osteomalacia rickets and diabetes 25-OH Vitamin D2 and 25-OH Vitamin D3 as vitamin D metabolites are measured in human serum to evaluate vitamin D level Vitamin D supplements are considered as an effective way to treat or to prevent the diseases
Medchemexpress LLC Ranitidine-d6 hydrochloride | 1185238-09-8 | 97.0% | 1 MG
Ranitidine-d6 hydrochloride is the deuterium labeled Ranitidine hydrochloride (HY-B0281A). Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. It antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride also inhibits breast tumor development and spread in mice.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Target: H2 receptor.
Medchemexpress LLC O-phthalaldehyde-d6 | 68234-47-9 | 140.17 g·mol⁻¹ | C8D6O2 | 1mg
Phthalaldehyde-d6 is the deuterium labeled Phthalaldehyde (HY-W012669) Phthalaldehyde is a biochemical assay reagent which modifies the amino acid and measure the derivative through HPLC Phthalaldehyde forms a fluorescent compound with -amino group[1][2]
Sigma Aldrich Fine Chemicals Biosciences 1,4-Diaminobutane-2,2,3,3-d4 dihydrochloride 98 atom % D | 88972-24-1 | MFCD01075442 | 500MG
1,4-Diaminobutane-2,2,3,3-d4 dihydrochloride 98 atom % D | Mol Wt: 165.1 | 88972-24-1 | MFCD01075442 | 500MG
Medchemexpress LLC Rutin-d3 | 613.54 | C27H27D3O16 | 2.5mg
Rutin-d3 is a deuterated labeled Rutin-d3[1]
Sigma Aldrich Fine Chemicals Biosciences Biotin 2233 d4 98 atom D1MG
Biotin is a water-soluble vitamin B which is also known as vitamin B7. It is involved in the synthesis of fatty acids and gluconeogenesis. Biotin is found in plants and animals. Its deficiency causes retardation in growth alopecia and neurological impairment in humans and animals.Biotin-2AE 2AE 3AE 3AE-d4 is an isotope of vitamin B7 wherein C-2AE C-2AE C-3AE C-3AE protons are replaced by deuterium.
Medchemexpress LLC Propranolol-d7 | 98897-23-5 | 98.55% | 1 MG
Deuterium-labeled Propranolol is a nonselective β-adrenergic receptor antagonist, exhibiting high affinity for both β1AR and β2AR. It is utilized in research for various cardiovascular conditions and as a tracer in drug development studies. The incorporation of stable heavy isotopes can influence the pharmacokinetic and metabolic profiles of compounds.
- Nonselective β-adrenergic receptor antagonist with high affinity for β1AR and β2AR.
- Used in the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.
- Functions as a tracer and an internal standard for quantitative analysis in techniques like NMR, GC-MS, or LC-MS.
- Deuterium labeling can impact pharmacokinetic and metabolic profiles.
Medchemexpress LLC 4-Oxo-2,2,6,6-tetramethylpiperidine-d16-1-15N-1-oxyl | 80404-14-4 | >98.0% | 187.32 g/mol | 15NC9D16O2 | 5 MG
Tempone-15N,d16 is an isotopically labeled nitroxide (15N and deuterium d16) derivative of Tempone provided for analytical and research use. It is used as a tracer and as an internal standard for quantitative analyses by NMR, GC-MS, and LC-MS. CAS 80404-14-4; molecular formula 15NC9D16O2; molecular weight 187.32 g/mol.
- Isotopically labeled for unambiguous tracking in mass spectrometry.
- Suitable as an internal standard for quantitative NMR, GC-MS, and LC-MS.
- High isotopic enrichment and chemical purity (>98%).
- Supplied in small, ready-to-use quantities for analytical workflows.
- Stable nitroxide radical useful for spin-label and tracer applications.
Medchemexpress LLC Ethylene carbonate-d4 | 362049-63-6 | MFCD01861595 | 99.2% | 92.09 | C3D4O3 | 1g
Ethylene carbonate-d4 is the deuterium labeled Ethylene carbonate[1]
Cayman Chemical ncrosulfonamIde-d4 1mg
An internal standard for the quantification of necrosulfonamide by GC- or LC-MS
Medchemexpress LLC Ronidazole-d3 | 1015855-87-4 | MFCD09265285 | 5 MG
Ronidazole-d3 is the deuterium-labeled version of Ronidazole. It is an effective orally active antiprotozoal and anti-microbial agent used as a veterinary agent against Tritrichomonas foetus in cat models and in research for histomoniasis and swine dysentery.
- Can be used as a tracer.
- Can serve as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes can be incorporated into drug molecules as tracers for quantitation during drug development.
- Deuteration has potential to influence pharmacokinetic and metabolic profiles of drugs.
![Revvity Health Sciences Inc Deoxy-D-glucose, 2-[1-14C]-, Aqueous Solution, 250 µCi (9.25 MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3385264.jpg-250.jpg)
Revvity Health Sciences Inc Deoxy-D-glucose, 2-[1-14C]-, Aqueous Solution, 250 µCi (9.25 MBq)
Deoxy-D-glucose, 2-[1-14C]-, Aqueous Solution, 250 µCi (9.25 MBq)
Medchemexpress LLC Lactate-d4 sodium | 344299-52-1 | 99.0% | 5 MG
Lactic acid-d4 sodium (60% in water) is a deuterium-labeled form of lactic acid sodium. The unlabeled compound is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator that induces lysine residue lactylation. It serves as a glycolysis end-product, bridging glycolysis and oxidative phosphorylation. It is also recognized as an oncometabolite with an immune-protective role in anti-tumor immunity and possesses antimicrobial activity, making it suitable as a food preservative.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Fmoc-Gly-OH-13C2,15N | 285978-13-4 | 99.6% | 300.28 | C15(13C2)H15(15N)NO4 | 5mg
Fmoc-Gly-OH-13C2 15N (Fmoc glycine-13C2 15N) is a 15N-labeled and 13C-labled Fmoc-Gly-OH (HY-Y1250) Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative can be used for the synthesis of compounds[1]